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Commission on Nomenclature of Organic Chemistry

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Commission on Nomenclature of Organic Chemistry
NameCommission on Nomenclature of Organic Chemistry
Formation1921
HeadquartersZürich
Parent organizationInternational Union of Pure and Applied Chemistry
PurposeStandardization of organic chemical nomenclature

Commission on Nomenclature of Organic Chemistry is a specialized international body responsible for developing systematic naming conventions for organic compounds, active in codifying rules used by chemists worldwide. The commission interacts with major scientific institutions such as Royal Society of Chemistry, American Chemical Society, Max Planck Society, École Normale Supérieure, and Chinese Academy of Sciences and its work influences publications like Journal of the American Chemical Society, Angewandte Chemie, Nature Chemistry, Science, and Royal Society Open Science.

History

The commission was established in the early 20th century amid efforts by organizations including International Union of Pure and Applied Chemistry, Chemical Society (London), Deutsche Chemische Gesellschaft, American Chemical Society, and Società Chimica Italiana to harmonize nomenclature after conferences such as the Paris Conference (1920) and meetings involving delegates from University of Cambridge, University of Oxford, Harvard University, Massachusetts Institute of Technology, and University of Berlin. Throughout the 20th century the commission coordinated with figures and bodies like Emil Fischer, A. R. Katritzky, Linus Pauling, Pauling's Laboratory, Royal Institution, and Institute of Chemistry (India) during major updates following gatherings at venues such as IUPAC General Assembly, Gordon Research Conferences, Cold Spring Harbor Laboratory, and Nobel Symposiums. Postwar developments saw collaboration with United Nations Educational, Scientific and Cultural Organization, European Chemical Society, International Council for Science, National Academy of Sciences (United States), and Académie des sciences to address emerging compound classes discovered at institutions like California Institute of Technology, Scripps Research, and Weizmann Institute of Science.

Structure and Membership

The commission's governance aligns with bodies such as International Union of Pure and Applied Chemistry, IUPAC Bureau, Division of Organic Chemistry (IUPAC), Executive Committee, Standing Committees, and national adhering organizations including Royal Society of Chemistry, American Chemical Society, Deutsche Forschungsgemeinschaft, Conseil National de la Recherche Scientifique, and Japan Society for the Promotion of Science. Membership typically comprises delegates nominated by institutions like University of Cambridge, Massachusetts Institute of Technology, ETH Zurich, Université Paris-Saclay, and University of Tokyo, and includes past contributors such as Robert Robinson, Ernest R. Baldwin, Victor Grignard, Heinrich Wieland, and contemporary representatives from Max Planck Institute for Coal Research, California Institute of Technology, and National Institutes of Health. Administrative interactions are modeled on protocols used by International Standards Organization, World Health Organization, European Commission, Council of Europe, and United Nations for international scientific committees.

Functions and Activities

The commission drafts systematic rules and recommendations in collaboration with editorial teams from Chemistry World, Chemical Reviews, Pure and Applied Chemistry, Accounts of Chemical Research, and European Journal of Organic Chemistry; organizes symposia at gatherings such as IUPAC Congress, Gordon Research Conferences, International Conference on Chemical Nomenclature, American Chemical Society National Meeting, and EuChemS Congress; and adjudicates name proposals submitted by researchers at Stanford University, Columbia University, University of California, Berkeley, Imperial College London, and University of Melbourne. It also liaises with standards bodies like International Organization for Standardization, American National Standards Institute, British Standards Institution, Deutsches Institut für Normung, and Japanese Industrial Standards Committee to implement approved nomenclature in databases maintained by National Center for Biotechnology Information, Chemical Abstracts Service, PubChem, ChEMBL, and Reaxys.

Nomenclature Recommendations and Publications

Key outputs include recommendations published in periodicals such as Pure and Applied Chemistry, monographs comparable to works by IUPAC Blue Book, treatises akin to writings of Robert Robinson and Victor Grignard, and updates disseminated through outlets like Royal Society Publishing, Wiley-VCH, Springer Nature, Elsevier, and Taylor & Francis. The commission's published rules cover topics addressed in landmark texts from institutions like University of Illinois Urbana-Champaign, University of Wisconsin–Madison, University of Chicago, Yale University, and Princeton University and are reflected in databases used by European Bioinformatics Institute, Swiss Institute of Bioinformatics, Riken, National Institute of Standards and Technology, and Brookhaven National Laboratory.

Relationship with IUPAC and Other Bodies

Operating under the auspices of International Union of Pure and Applied Chemistry, the commission coordinates with IUPAC divisions such as the Division of Organic and Biomolecular Chemistry, the Committee on Publications and Cheminformatics Data Standards, and the IUPAC Bureau while maintaining formal links to national societies including Royal Society of Chemistry, American Chemical Society, Deutsche Chemische Gesellschaft, Sociedad Química de México, and Indian Chemical Society. It collaborates with research centers like Max Planck Institutes, Lawrence Berkeley National Laboratory, Brookhaven National Laboratory, CNRS, and CNR and contributes to standards discussions at International Organization for Standardization, World Health Organization, Food and Agriculture Organization, and European Medicines Agency.

Impact and Criticisms

The commission's standards are widely adopted by publishers such as Elsevier, Wiley, Springer Nature, ACS Publications, and Royal Society of Chemistry and by databases including Chemical Abstracts Service, PubChem, Reaxys, ChEMBL, and SciFinder, shaping curricula at universities like Harvard University, University of Cambridge, MIT, ETH Zurich, and University of Tokyo. Criticisms from scholars affiliated with University of California, Berkeley, University of Chicago, Columbia University, Imperial College London, and Tokyo Institute of Technology argue that some recommendations lag behind nomenclature needs for subjects studied at Genentech, Pfizer, Novartis, Roche, and Merck & Co. and from research areas promoted by CRISPR Research Community, Synthetic Biology Community, Materials Research Society, and Computational Chemistry Association; these critiques have prompted discussions at venues like IUPAC Congress, Gordon Research Conferences, Royal Society Symposiums, and European Chemical Congress.

Category:Chemical nomenclature