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Uppsala Multiscale Center

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Uppsala Multiscale Center
NameUppsala Multiscale Center
Established2010
LocationUppsala, Sweden
TypeResearch center
AffiliationUppsala University

Uppsala Multiscale Center is a multidisciplinary research institution based in Uppsala, Sweden, focused on multiscale modeling, simulation, and experimental validation across physical, biological, and materials sciences. The center integrates approaches from computational physics, systems biology, nanotechnology, and environmental science to connect phenomena spanning atomic, molecular, cellular, and macroscopic scales. It functions as a hub linking university departments, national laboratories, and international research programs to address complex problems in energy, health, and materials.

Overview

The center brings together researchers from Uppsala University, Royal Institute of Technology, Karolinska Institutet, Stockholm University, and other European institutions such as University of Cambridge, ETH Zurich, Max Planck Society, CNRS, and CERN-affiliated groups. Key areas intersect with initiatives by European Research Council grantees, Horizon Europe networks, and collaborations with industry partners including Volvo Group, ABB, Ericsson, and Siemens. The center promotes open science through links with repositories like Zenodo and engages with standards organizations such as ISO and IEEE. Facilities support integration with national infrastructures like Swedish National Infrastructure for Computing and European facilities including PRACE and EMBL.

History

Founded in 2010 through a consortium led by Uppsala University and endorsed by the Swedish Research Council and local government of Uppsala Municipality, the center expanded during the 2010s via strategic partnerships with the Wallenberg Foundation and participation in projects funded by European Commission frameworks. Early collaborations involved groups from Harvard University and Massachusetts Institute of Technology on multiscale materials modeling and with Karolinska Institutet on multiscale biomedical simulations. Notable milestones include establishing a computational cluster in collaboration with Linköping University and hosting workshops featuring speakers from Stanford University, Princeton University, Imperial College London, and University of California, Berkeley.

Research Themes and Programs

Programs are organized around thematic clusters that align with international research priorities such as those of United Nations Environment Programme and World Health Organization. Principal themes include multiscale materials design connecting research by groups like Materials Project and National Institute of Standards and Technology; multiscale systems biology linked to research at European Molecular Biology Laboratory and Wellcome Trust initiatives; and multiscale geoscience informed by work at American Geophysical Union and Geological Survey of Sweden. Programs draw funding from agencies including Vinnova, NordForsk, and NASA collaborations for planetary materials research. Translational efforts connect to start-ups incubated with partners such as STING and Karolinska Innovation.

Facilities and Infrastructure

Physical and computational infrastructure includes cleanroom laboratories comparable to those at Nanoscience Center, University of Jyväskylä, advanced microscopy suites similar to European Synchrotron Radiation Facility beamline collaborations, and high-performance computing resources integrated with SNIC and EuroHPC. Instrumentation supports links to experimental platforms at MAX IV Laboratory, ESRF, and cryo-electron microscopy centers associated with Thermo Fisher Scientific instrumentation. The center maintains data management pipelines compatible with FAIR principles advocated by ELIXIR and software stacks interoperable with community codes such as LAMMPS, GROMACS, OpenFOAM, and Quantum ESPRESSO.

Collaborations and Partnerships

Collaborative networks include academic consortia like Gothenburg Research Institute partnerships, EU-funded consortia under Marie Skłodowska-Curie Actions, and industry alliances with Scania AB and AstraZeneca. The center engages in bilateral agreements with research centers including Lawrence Berkeley National Laboratory, Argonne National Laboratory, Rutherford Appleton Laboratory, and Paul Scherrer Institute. It contributes to standards and benchmarking initiatives coordinated by International Energy Agency and participates in challenge-driven calls from Graphene Flagship and Human Frontier Science Program.

Education and Training

Training programs offer doctoral and postdoctoral fellowships co-supervised by faculty from Uppsala University, Lund University, and Chalmers University of Technology. Short courses and summer schools feature lecturers from University of Oxford, Yale University, Columbia University, and Delft University of Technology, and include modules on multiscale modeling using toolkits developed in collaboration with European Bioinformatics Institute and OpenAIRE. Outreach engages secondary education via partnerships with Uppsala University Museum and public science events aligned with Nobel Prize-related programming in Stockholm.

Governance and Funding

Governance is overseen by a board comprising representatives from Uppsala University, regional government bodies of Uppsala County, and international advisors from institutions such as Royal Society fellowship members and recipients of awards like the Turing Award and Nobel Prize laureates on advisory panels. Funding is a mix of competitive grants from Swedish Research Council, philanthropic support from foundations like Knut and Alice Wallenberg Foundation, and industry contracts with multinational corporations including GE Healthcare and BASF. Strategic reviews are coordinated with stakeholders including European Commission program officers and national funding agencies.

Category:Research institutes in Sweden