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| University of Michigan Institute for Clinical and Health Research | |
|---|---|
| Name | University of Michigan Institute for Clinical and Health Research |
| Established | 2006 |
| Type | Research institute |
| Affiliation | University of Michigan |
| Director | James C. Kohn |
| Location | Ann Arbor, Michigan |
| Country | United States |
University of Michigan Institute for Clinical and Health Research is an academic research institute based in Ann Arbor, Michigan affiliated with the University of Michigan. It serves as a hub for translational science linking clinical investigation, community engagement, and methodological innovation across academic medicine. The institute coordinates interdisciplinary teams involving faculty from medicine, public health, nursing, pharmacy, engineering, and social science specialties to accelerate research from bench to bedside.
The institute was founded amid national initiatives such as the Clinical and Translational Science Award program and parallel efforts at institutions like Johns Hopkins University, University of California, San Francisco, Harvard Medical School, and Mayo Clinic to strengthen translational research infrastructure. Early collaborations connected investigators from Michigan Medicine, School of Public Health (University of Michigan), College of Engineering (University of Michigan), School of Nursing (University of Michigan), and external partners including Centers for Disease Control and Prevention, National Institutes of Health, and regional healthcare systems. Over time the institute expanded programs modeled after consortia at Stanford University, University of Pennsylvania, Yale University, and Cleveland Clinic. Its evolution reflected trends led by agencies such as the National Center for Advancing Translational Sciences and policy dialogues involving Institute of Medicine convenings.
The institute's mission aligns with priorities promoted by organizations like the National Institutes of Health, Robert Wood Johnson Foundation, and Patient-Centered Outcomes Research Institute: to support clinical and health research that improves patient outcomes and population health. Governance typically involves an executive leadership team, advisory boards with members drawn from Michigan Medicine, School of Public Health (University of Michigan), Office of Research (University of Michigan), and external stakeholders from institutions such as Blue Cross Blue Shield Association and regional hospital systems. Administrative cores coordinate regulatory affairs, biostatistics support from units akin to Department of Biostatistics (University of Michigan), informatics services comparable to National Library of Medicine, and community engagement modeled on Community-Campus Partnerships for Health.
Programs emphasize translational pipelines similar to those at Vanderbilt University Medical Center and University of Washington Medical Center, spanning therapeutics, health services research, implementation science, and population health. Centers have included thematic initiatives in precision medicine echoing work at Broad Institute, comparative effectiveness research paralleling Duke Clinical Research Institute, pragmatic trials like those at Kaiser Permanente, and digital health projects referencing efforts at Massachusetts Institute of Technology. Multidisciplinary teams link investigators from the Medical School (University of Michigan), School of Pharmacy (University of Michigan), Taubman College of Architecture and Urban Planning, and external partners including Spectrum Health and Henry Ford Health System.
Training programs mirror national models such as the NIH Clinical Research Training Program and interprofessional curricula at University of Washington. The institute supports career development awards, postdoctoral fellowships, and mentored K-style programs staffed by faculty from Department of Internal Medicine (University of Michigan), Department of Family Medicine (University of Michigan), and allied health departments. It hosts workshops on study design inspired by resources from CONSORT and methods courses similar to those at Harvard T.H. Chan School of Public Health, while facilitating training collaborations with provincial centers like Michigan Institute for Clinical & Health Research peer institutions across the Big Ten Academic Alliance.
The institute maintains partnerships with clinical systems including Michigan Medicine, St. Joseph Mercy Health System, Trinity Health, and community organizations such as Washtenaw County Health Department and local chapters of American Cancer Society. Community engagement strategies draw on best practices from Community-Based Participatory Research exemplars at University of California, Los Angeles and University of New Mexico. Collaborations with patient advocacy groups like American Heart Association, Alzheimer's Association, and American Diabetes Association inform study priorities and dissemination approaches.
Funding streams include federal awards from National Institutes of Health, competitive grants from Patient-Centered Outcomes Research Institute, foundation support from entities such as Robert Wood Johnson Foundation and W.K. Kellogg Foundation, and industry-sponsored research with partners like Pfizer, Johnson & Johnson, and Medtronic. The institute administers institutional pilot grants and seed funding modeled on programs at Emory University to catalyze multi-investigator proposals to national solicitations including R01-equivalent mechanisms and NIH cooperative agreements.
Core resources include biostatistics and epidemiology cores akin to those at Fred Hutchinson Cancer Research Center, clinical research units comparable to Clinical Translational Research Center (CTRC), biorepository facilities similar to UK Biobank workflows, and informatics platforms that parallel i2b2 and Research Electronic Data Capture. Physical infrastructure leverages hospital-based clinical research spaces at C. S. Mott Children's Hospital and laboratory collaborations with Life Sciences Institute (University of Michigan). The institute provides regulatory support, training in Good Clinical Practice, and access to community registries and data resources that facilitate longitudinal cohort studies.
Category:Medical research institutes Category:University of Michigan