Science Signaling

Science Signaling
Title	Science Signaling
Discipline	Cell signaling, Molecular biology, Systems biology
Abbreviation	Sci. Signal.
Publisher	American Association for the Advancement of Science
Country	United States
History	2008–present
Frequency	Weekly
Openaccess	Hybrid

Science Signaling

Science Signaling is a peer-reviewed journal focusing on cellular signaling, regulatory networks, and signal transduction in health and disease. It publishes research articles, reviews, and perspectives that connect molecular mechanisms to physiological and pathological contexts, engaging readers across institutions such as Harvard University, Stanford University, Massachusetts Institute of Technology, and Johns Hopkins University.

Overview

Science Signaling covers experimental and theoretical work on signaling pathways, network dynamics, and communication among cells and tissues. Contributors include investigators from Cold Spring Harbor Laboratory, Max Planck Society, European Molecular Biology Laboratory, Broad Institute, and Weizmann Institute of Science. The journal often places studies alongside commentary from scholars at University of Cambridge, University of Oxford, Yale University, University of California, San Francisco, and University of Chicago. Topics intersect with research from laboratories led by figures associated with Howard Hughes Medical Institute, National Institutes of Health, Wellcome Trust, and Gordon and Betty Moore Foundation.

History and Development

Launched in 2008 by the American Association for the Advancement of Science, the journal emerged amid broader shifts in publishing exemplified by titles such as Science, Nature, Cell, and Proceedings of the National Academy of Sciences. Its formation paralleled developments at institutions like Cold Spring Harbor Laboratory Press and societies such as The Royal Society and European Molecular Biology Organization. Editors and advisory board members have included researchers affiliated with Carnegie Institution for Science, Salk Institute, Rockefeller University, Princeton University, and Imperial College London. Over time, editorial policies adapted in response to initiatives from Committee on Publication Ethics, funding mandates from National Science Foundation and clinical priorities articulated by World Health Organization.

Editorial Scope and Content

The journal's scope spans molecular receptors, kinase cascades, second messengers, transcriptional networks, and community-level signaling in models ranging from Escherichia coli to Mus musculus and human studies. Articles frequently cite methodologies developed at Cold Spring Harbor Laboratory, techniques refined at EMBL-EBI, and computational approaches from groups at Santa Fe Institute and Institute for Systems Biology. Reviews and perspectives draw on work by investigators from California Institute of Technology, University of Toronto, ETH Zurich, Peking University, and Seoul National University. Special issues and commentaries have involved collaborations with organizations such as Gates Foundation, European Research Council, and American Cancer Society.

Abstracting, Indexing, and Impact

Science Signaling is indexed in major databases including PubMed, Web of Science, Scopus, and Medline, and its articles contribute to citation networks analyzed by groups at Clarivate Analytics and Elsevier. The journal's impact metrics are used in assessments by universities like University of Pennsylvania, Columbia University, Duke University, and funding agencies including National Institutes of Health and European Commission. Bibliometric studies from Institute for Scientific Information and Leiden University examine its citation influence relative to journals such as Nature Communications and Cell Reports.

Notable Research and Contributions

Published work has illuminated pathways involving receptor tyrosine kinases studied in labs at Memorial Sloan Kettering Cancer Center and Dana-Farber Cancer Institute, GPCR signaling researched at Oxford University and University College London, and innate immune signaling traced to teams at University of Tokyo and Imperial College London. Landmark articles have influenced clinical research at Mayo Clinic and translational programs at Mount Sinai Health System and Cleveland Clinic. The journal has disseminated advances in CRISPR-related signaling studies linked to groups at Broad Institute and University of California, Berkeley, and systems-level analyses aligned with work from MIT and Harvard Medical School.

Access and Publication Model

Published by the American Association for the Advancement of Science, the journal operates a hybrid model combining subscription access with open-access options supported by article processing charges recognized by funders such as Wellcome Trust, Bill & Melinda Gates Foundation, and the National Institutes of Health. The editorial and peer-review processes align with guidelines from Committee on Publication Ethics and publishing standards observed by Elsevier and Springer Nature imprints. Authors affiliated with institutions including Yale University, University of Washington, University of Michigan, and University of California, San Diego routinely publish under this model.

Category:Academic journals Category:Biology journals