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Scheuermann's disease

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Scheuermann's disease
NameScheuermann's disease
FieldOrthopedics
OnsetAdolescence
DurationVariable
CausesMultifactorial
TreatmentConservative, surgical

Scheuermann's disease is a structural spinal disorder characterized by anterior wedging of vertebral bodies leading to kyphotic deformity, typically presenting during adolescence. It is managed across specialties including Orthopedics, Physical therapy, and Radiology, with involvement from institutions such as Mayo Clinic, Johns Hopkins Hospital, and Great Ormond Street Hospital for complex care. Historical descriptions trace to early 20th-century clinicians and remain relevant in modern guidelines from organizations like the American Academy of Orthopaedic Surgeons and the British Orthopaedic Association.

Overview

Scheuermann's disease classically produces a rigid thoracic kyphosis caused by endplate irregularities and vertebral wedging during growth. Presentation prompts evaluation by specialists at centers such as Hospital for Special Surgery and may require imaging from departments like Massachusetts General Hospital's Radiology service. Management pathways involve multidisciplinary teams including clinicians at Cleveland Clinic and researchers affiliated with universities such as Harvard University, Imperial College London, and University of Toronto.

Signs and symptoms

Adolescents often report postural changes, back pain, and reduced spinal flexibility leading families to seek care from pediatricians associated with Great Ormond Street Hospital, Children's Hospital of Philadelphia, or community clinics. Physical findings include fixed thoracic kyphosis, compensatory lumbar lordosis, and possible fingertip-to-floor discrepancy, evaluated by clinicians influenced by protocols from American Academy of Pediatrics, Royal College of Physicians, and National Institute for Health and Care Excellence. Symptoms can impair participation in athletics overseen by organizations like FIFA, International Olympic Committee, and national sports federations.

Causes and risk factors

Etiology is multifactorial with proposed genetic contributions studied at institutions such as Karolinska Institute, University of Oslo, and Uppsala University, while mechanical and biochemical hypotheses have been investigated by researchers at Stanford University, University of California, San Francisco, and McGill University. Risk factors include adolescent growth spurts, family history noted in cohorts from University of Washington and University of Michigan, and activities with repetitive spinal loading examined in sports medicine centers like Aspetar and the Aspire Academy. Epidemiologic research has been published in journals tied to societies such as the American Orthopaedic Society for Sports Medicine and the Scoliosis Research Society.

Diagnosis

Diagnosis relies on history, physical examination, and imaging—plain radiographs demonstrating wedging of three or more vertebrae are interpreted using criteria standardized in studies from Mayo Clinic, Washington University in St. Louis, and Johns Hopkins Hospital. Advanced imaging including MRI is used to assess disc and endplate changes at centers like Mount Sinai Health System and UCLA Health. Differential diagnosis includes conditions evaluated by experts at Cincinnati Children’s Hospital Medical Center and institutions researching congenital and neuromuscular scoliosis, such as Shriners Hospitals for Children.

Treatment

Conservative treatment—observation, physiotherapy, bracing, and analgesia—is commonly initiated in collaboration with teams at Karolinska University Hospital, Guy's and St Thomas' NHS Foundation Trust, and university clinics like University College London Hospitals. Bracing regimens derive from protocols trialed at Scoliosis Research Society-affiliated centers and pediatric orthopedic units including Texas Scottish Rite Hospital for Children. Surgical correction, such as posterior spinal fusion, is reserved for severe deformity and performed at specialized centers like Hospital for Special Surgery, Texas Back Institute, and university hospitals including Massachusetts General Hospital and Rothman Orthopaedic Institute.

Prognosis and complications

Long-term outcomes vary; many individuals experience reduced symptoms with skeletal maturity, as reported in longitudinal cohorts from Duke University School of Medicine, University of Pittsburgh Medical Center, and Vanderbilt University Medical Center. Potential complications include chronic back pain, cosmetic concerns, and, rarely, neurologic compromise prompting referrals to neurosurgical services at Barrow Neurological Institute and Johns Hopkins Hospital. Quality-of-life impacts have been assessed in studies associated with World Health Organization initiatives and patient advocacy groups such as the Scoliosis Association UK.

Epidemiology

Prevalence estimates differ by population and methodology, documented in population studies from Sweden, Norway, United States, Japan, and Brazil. Reported prevalence ranges commonly between 0.4% and 8% in adolescent cohorts studied at universities including University of Copenhagen, Oslo University Hospital, Stanford University School of Medicine, and University of São Paulo. Male predominance and peak incidence during puberty are consistent findings across registries maintained by orthopedic societies like the British Scoliosis Society and the Scoliosis Research Society.

Category:Spine disorders