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Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center

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Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center
NameLouis A. Simpson and Kimberly K. Querrey Biomedical Research Center
LocationChicago, Illinois, United States
Completion date2019
OwnerNorthwestern University
ArchitectPerkins+Will
Floor count10
Floor area600000

Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center is a biomedical research facility affiliated with Northwestern University and located on the campus associated with Feinberg School of Medicine in Chicago, Illinois. The center consolidates basic science, translational research, and clinical investigation in a single structure designed to accelerate collaboration among investigators across disciplines such as Cancer Research Institute, Institute for Scientific Information-linked programs, and centers aligned with national priorities like those of the National Institutes of Health and National Science Foundation. The building opened in the late 2010s as part of a broader expansion of biomedical infrastructure connected to urban research ecosystems including partnerships with institutions such as Princeton University, Harvard University, and industry partners headquartered in Northwestern Medicine networks.

Design and Architecture

The center was designed by Perkins+Will in collaboration with institutional planners from Northwestern University and consultants experienced with facilities from projects at Massachusetts Institute of Technology, Johns Hopkins University, and University of California, San Francisco. The architecture emphasizes integrated laboratory floors, core facilities, and shared collaboration spaces, drawing on precedents from Salk Institute-inspired planning and the organizational strategies used at Broad Institute and Cold Spring Harbor Laboratory. Structural and mechanical systems incorporate approaches advocated by American Institute of Architects standards and follow sustainability practices similar to Leadership in Energy and Environmental Design projects implemented at University of Chicago and Yale University. Circulation, daylighting, and lab adjacency were informed by contemporary case studies at Stanford University and Columbia University research centers.

History and Development

Planning for the center involved leadership from administrators at Northwestern University, fundraisers familiar with campaigns like those run by University of Pennsylvania and Duke University, and scientific advisors with experience at National Institutes of Health-funded institutes and the Howard Hughes Medical Institute. Major milestones included schematic design phases influenced by collaborations with investigators from Brigham and Women's Hospital, procurement processes paralleling projects at Mayo Clinic and Cleveland Clinic, and construction backed by donors with philanthropic models similar to benefactions to Johns Hopkins Hospital and Memorial Sloan Kettering Cancer Center. The ribbon-cutting followed a period of recruitment of faculty with prior appointments at University of California, Berkeley, University of Michigan, Columbia University, and international partnerships reminiscent of exchanges with University of Cambridge and Imperial College London.

Facilities and Research Focus

The building houses wet laboratories, imaging suites, high-throughput sequencing cores, biostatistics groups, and clinical translational spaces akin to facilities at Fred Hutchinson Cancer Research Center and Scripps Research. Research themes integrated include oncology programs comparable to projects at Dana-Farber Cancer Institute, immunology efforts paralleling work at La Jolla Institute for Immunology, neurodegeneration studies with links to methods used at National Institute on Aging, and cardiovascular translational research reflecting priorities at American Heart Association-aligned centers. Core resources include cryo-electron microscopy platforms similar to those deployed at Brookhaven National Laboratory, single-cell genomics facilities like those at Broad Institute, and data science nodes interfacing with infrastructures used by Google DeepMind collaborators and computational biology groups at New York University.

Funding and Philanthropy

The project was financed through a mix of private philanthropy, institutional capital campaigns, and competitive grants from agencies such as the National Institutes of Health and foundations with funding patterns resembling those of Gordon and Betty Moore Foundation and Rockefeller Foundation. Major gifts were modeled on transformational donations like those to Stanford University and Harvard Medical School and coordinated by development officers experienced with campaigns at Yale University and Columbia University. Endowments and pilot funding support internal seed programs that mirror initiatives at HHMI and grant partnerships with corporate research entities similar to collaborations between Pfizer and academic laboratories.

Notable Researchers and Collaborations

Faculty recruited to the center include investigators with backgrounds at Harvard University, Princeton University, MIT, Johns Hopkins University, and international scholars from Max Planck Society-affiliated institutes and Karolinska Institute. Collaborative agreements extend to clinical partners such as Northwestern Memorial Hospital, translational networks like Clinical and Translational Science Awards hubs, and industry partnerships comparable to those with major biotechnology companies including Amgen, Genentech, and Regeneron. Multi-institutional projects involve consortia modeled on efforts like the Human Genome Project, multi-omics initiatives following examples from the Cancer Genome Atlas, and public-private partnerships inspired by collaborations between NIH and private foundations.

Awards and Recognition

The center's design and research impact have been recognized by organizations paralleling the American Institute of Architects and awards similar to those given by the Association of American Medical Colleges for innovation in biomedical infrastructure. Research conducted at the facility has contributed to publications in journals with reputations akin to Nature, Science, and Cell, and investigators have received honors comparable to Lasker Award-level recognition, fellowships similar to those from the Howard Hughes Medical Institute, and grants from entities like the Gates Foundation and the National Science Foundation.

Category:Northwestern University Category:Research institutes in Illinois