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| Istituto Pasteur-Fondazione Cenci Bolognetti | |
|---|---|
| Name | Istituto Pasteur-Fondazione Cenci Bolognetti |
| Established | 20th century |
| Location | Rome, Italy |
| Type | Research institute |
| Affiliations | Sapienza University of Rome |
Istituto Pasteur-Fondazione Cenci Bolognetti is an Italian biomedical research institute based in Rome connected to Sapienza University of Rome and engaged in translational science, clinical research, and postgraduate education. The institute operates within networks linking University of Rome Tor Vergata, Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, Ospedale San Camillo-Forlanini, Policlinico Umberto I and international centers such as Institut Pasteur, Centers for Disease Control and Prevention, Wellcome Trust, and European Molecular Biology Laboratory. Its programs intersect with initiatives from Ministry of Health (Italy), European Commission, and foundations including Cenci Bolognetti Foundation, Bill & Melinda Gates Foundation, Cariplo Foundation, and Howard Hughes Medical Institute.
The institute traces roots to collaborations among Sapienza University of Rome, the Italian Red Cross, and private patrons like Cenci Bolognetti Foundation and municipal entities in Rome, aligning with historic institutions such as Istituto Superiore di Sanità, Accademia dei Lincei, Fondazione Veronesi and connections to projects funded through Horizon Europe, European Research Council, and legacy networks involving Institut Pasteur, Pasteur Institute of Paris, Max Planck Society, National Institutes of Health, and Wellcome Trust. Early phases involved partnerships with clinical hubs including Ospedale Pediatrico Bambino Gesù, Policlinico Sant'Orsola-Malpighi, Istituto Ortopedico Rizzoli and collaborations with international laboratories such as Karolinska Institutet, University of Cambridge, Harvard Medical School, and Johns Hopkins University. Over decades the institute engaged in projects associated with World Health Organization, UNICEF, and European frameworks like Erasmus+ and COST actions, while hosting visiting scholars from Columbia University, Imperial College London, University of Oxford, and Yale University.
The institute's mission emphasizes translational work bridging Sapienza University of Rome clinical departments, public health agencies like Istituto Superiore di Sanità, and research consortia including European Research Council and Horizon Europe grants, targeting infectious diseases, immunology, molecular genetics, and neurodegeneration. Research themes intersect with studies from Institut Pasteur, Wellcome Trust, Bill & Melinda Gates Foundation, and collaborative trials with World Health Organization initiatives, spanning vaccinology, antimicrobial resistance, cell biology, and systems biology aligned with methodologies developed at European Molecular Biology Laboratory, Max Planck Society, and Cold Spring Harbor Laboratory. The institute emphasizes translational pipelines connecting to clinical sites such as Policlinico Umberto I, Ospedale San Giovanni Addolorata, and international trial networks coordinated with Centers for Disease Control and Prevention, European Centre for Disease Prevention and Control, and industry partners like Roche, Novartis, and Pfizer.
Facilities include molecular biology suites modeled after European Molecular Biology Laboratory standards, biosafety level units comparable to those at Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, imaging centers equipped as in Fondazione IRCCS Istituto Neurologico Carlo Besta, and biobanks following protocols of BBMRI-ERIC and European Genome-phenome Archive. Core platforms integrate technologies from Illumina, Thermo Fisher Scientific, and collaborations with making facilities similar to EMBL-EBI and computational hubs reminiscent of CINECA, Barcelona Supercomputing Center, and European Bioinformatics Institute. Laboratories host structural biology instruments related to methods from European Synchrotron Radiation Facility, proteomics units reflecting Max Planck Institute for Biochemistry practices, and cell therapy cleanrooms inspired by Fondazione Telethon programs.
Educational and clinical offerings coordinate with Sapienza University of Rome postgraduate courses, residency training across departments linked to Policlinico Umberto I, and fellowship exchanges with Institut Pasteur, Karolinska Institutet, Harvard Medical School, University College London, and University of Cambridge. Programs include joint degrees under frameworks like Erasmus Mundus and research doctorates connected to European Research Council grants, while continuing medical education collaborates with World Health Organization regional offices and professional bodies such as European Society of Clinical Microbiology and Infectious Diseases and European Academy of Neurology. Clinical trials are registered with networks involving ClinicalTrials.gov partners, coordinated with hospitals including Ospedale Pediatrico Bambino Gesù, Istituto Ortopedico Rizzoli, and international sites such as Mayo Clinic.
The institute maintains partnerships with national and international organizations including Institut Pasteur, Istituto Superiore di Sanità, European Molecular Biology Laboratory, Max Planck Society, Wellcome Trust, Bill & Melinda Gates Foundation, European Commission, European Centre for Disease Prevention and Control, World Health Organization, Centers for Disease Control and Prevention, Karolinska Institutet, University of Cambridge, Harvard Medical School, Johns Hopkins University, Imperial College London, University of Oxford, Columbia University, Yale University, Roche, Novartis, Pfizer, Telethon Foundation, Fondazione Veronesi, and regional hospitals like Policlinico Umberto I and Ospedale San Camillo-Forlanini. Scientific consortia include participation in Horizon Europe projects, European Research Council programs, Erasmus+ exchanges, and networks like BBMRI-ERIC and COST actions.
Leadership and affiliated scientists have included figures with ties to Sapienza University of Rome, visiting or collaborative appointments with Institut Pasteur, Karolinska Institutet, Harvard Medical School, Max Planck Society, European Molecular Biology Laboratory, Istituto Superiore di Sanità, and international research figures recognized by awards such as the Louis-Jeantet Prize for Medicine, Lasker Award, Wolf Prize in Medicine, and Gairdner Foundation International Award. The institute has hosted researchers who previously worked at Cold Spring Harbor Laboratory, Broad Institute, Wellcome Sanger Institute, EMBL-EBI, Johns Hopkins University, University of Cambridge, Imperial College London, and Yale University.
Funding streams combine grants from European Commission, European Research Council, Ministry of Health (Italy), Cenci Bolognetti Foundation, Fondazione Cariplo, Bill & Melinda Gates Foundation, Wellcome Trust, and industry partnerships with Roche, Novartis, and Pfizer, alongside philanthropic support resembling contributions from Telethon Foundation and Fondazione Veronesi. Governance structures connect to boards including representatives from Sapienza University of Rome, municipal authorities of Rome, and advisory panels with experts from Institut Pasteur, European Molecular Biology Laboratory, Max Planck Society, and Istituto Superiore di Sanità.