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European Antimicrobial Resistance Collaborating Network

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European Antimicrobial Resistance Collaborating Network
NameEuropean Antimicrobial Resistance Collaborating Network
AbbreviationEARCNet
Formation2018
TypeResearch network
HeadquartersBrussels
Region servedEurope
Leader titleDirector
Leader nameDr. Maria Jensen

European Antimicrobial Resistance Collaborating Network

The European Antimicrobial Resistance Collaborating Network is a transnational research and advocacy consortium focused on antimicrobial resistance initiatives across European Union, World Health Organization, European Centre for Disease Prevention and Control, Council of Europe, North Atlantic Treaty Organization, United Nations, European Commission, European Parliament, Organisation for Economic Co-operation and Development, G20, World Bank stakeholders. It engages institutions such as Charité – Universitätsmedizin Berlin, Institut Pasteur, Karolinska Institutet, University of Oxford, Imperial College London to coordinate surveillance, research, and policy translation across public health, veterinary, and agricultural sectors.

Background and Establishment

Founded in 2018 following stakeholder consultations with European Commission Directorates and the World Health Organization Regional Office for Europe, the network emerged from initiatives linked to the Global Action Plan on Antimicrobial Resistance, the One Health policy dialogues endorsed at meetings including World Health Assembly sessions and the G7 and G20 policy communiqués. Early convenings included representatives from European Centre for Disease Prevention and Control, Food and Agriculture Organization, World Organisation for Animal Health and major academic centers such as University of Copenhagen, University of Amsterdam, University of Edinburgh.

Mission and Objectives

The network's mission aligns with recommendations from World Health Organization, aiming to reduce antimicrobial resistance through integrated surveillance, capacity building, and evidence-based policy support, working with partners including European Medicines Agency, Food and Drug Administration, Public Health England, Robert Koch Institute, Santé publique France to harmonize approaches. Objectives emphasize strengthening laboratory capacity at centers like University College London Hospitals, advancing stewardship programs promoted by Danish Health Authority, and supporting regulatory alignment traceable to frameworks from the European Commission and the Council of the European Union.

Governance and Membership

Governance comprises a board featuring representatives from European Centre for Disease Prevention and Control, national public health institutes such as Robert Koch Institute, Instituto de Salud Carlos III, and academic leaders from Université PSL, Heidelberg University, Trinity College Dublin. Membership includes universities (e.g., University of Barcelona, University of Milan), hospitals (e.g., St Thomas' Hospital, Hôpital Saint-Louis), research bodies (Max Planck Society, Austrian Academy of Sciences), and NGOs like Médecins Sans Frontières, European Public Health Alliance, with advisory input from funders such as Wellcome Trust, Bill & Melinda Gates Foundation, and corporate partners including GlaxoSmithKline and Roche.

Programs and Activities

Programs span capacity building workshops with partners like European Society of Clinical Microbiology and Infectious Diseases, clinical guideline development akin to efforts by National Institute for Health and Care Excellence, antimicrobial stewardship campaigns modeled after CDC initiatives, and training exchanges with networks such as European Respiratory Society and European Society of Clinical Pharmacy. Activities include laboratory strengthening projects in collaboration with Institut Pasteur de Tunis affiliates, postgraduate fellowships linked to European Molecular Biology Laboratory, and annual symposia held alongside events like European Public Health Conference and Infectious Diseases Society of America meetings.

Research and Surveillance Initiatives

The network leads multicenter studies on resistance trends comparable to surveillance systems run by European Antimicrobial Resistance Surveillance Network partners, coordinates genomic epidemiology projects utilizing platforms from European Nucleotide Archive, and partners with initiatives such as Global Antimicrobial Resistance Surveillance System and the Human Microbiome Project. Research collaborations involve institutions including ETH Zurich, Polish Academy of Sciences, Sahlgrenska Academy and technology partners like Illumina and Oxford Nanopore Technologies to harmonize sequencing, bioinformatics, and data-sharing protocols consistent with standards from Committee on Publication Ethics.

Funding and Partnerships

Funding derives from mixed sources including grants from European Commission research programs such as Horizon 2020 and Horizon Europe, philanthropic awards from Wellcome Trust and Bill & Melinda Gates Foundation, contributions from national ministries like Ministry of Health (France), Bundesministerium für Gesundheit, and collaborative contracts with industry partners including Novartis and Sanofi. Partnerships extend to multilateral bodies such as World Health Organization, Food and Agriculture Organization, World Organisation for Animal Health, and regional entities like European Investment Bank to finance infrastructure and implementation projects.

Impact and Policy Influence

The network has contributed evidence cited in policy instruments by the European Commission and advisory reports to the World Health Organization, informed national action plans adopted by Sweden, Netherlands, and United Kingdom, and supplied data to harmonize regulatory guidance with agencies like European Medicines Agency and Food and Drug Administration. Outputs have been referenced in strategic documents from G20 health working groups and incorporated into procurement frameworks used by NATO medical services, influencing stewardship protocols at hospitals such as Guy's and St Thomas' NHS Foundation Trust and surveillance strategies employed by Agence nationale de sécurité du médicament et des produits de santé.

Category:Public health organizations Category:Antimicrobial resistance