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E288

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E288
NameE288

E288

E288 is a designation used in regulatory and industrial contexts to denote a specific food additive or compound. It appears in lists of additives, inventories of preservatives, and technical monographs, and is cited in standards, regulatory texts, and industry guidance documents. The designation is encountered in publications from agencies, trade associations, and scientific literature concerned with food safety, chemical manufacturing, and public health.

Identification and Nomenclature

E288 is recorded in additive catalogs alongside other European Food Additives and appears in cross-references maintained by entities such as European Food Safety Authority, Codex Alimentarius Commission, and national food standard agencies like Food Standards Agency and Federal Institute for Risk Assessment. Alternative identifiers include registry numbers assigned by chemical databases such as Chemical Abstracts Service, entries in PubChem, and listings in pharmacopoeias or technical compendia issued by organizations like United States Pharmacopeia or British Pharmacopoeia. Industrial producers, trade groups, and standard-setting bodies such as International Organization for Standardization and International Food Additives Council may use trade names or catalog numbers that correspond to the E288 code.

Chemical Properties and Structure

The compound associated with E288 is characterized by a defined molecular formula, molecular weight, and structural features documented in analytical chemistry references like IUPAC nomenclature guides, spectroscopic atlases, and monographs from Merck Index. Typical data include melting point, boiling point, solubility parameters, refractive index, and stability profiles under thermal, photolytic, and oxidative conditions. Structural elucidation is supported by techniques standardized by organizations such as American Society for Testing and Materials, including nuclear magnetic resonance as in publications from Royal Society of Chemistry, mass spectrometry entries in NIST databases, and infrared spectra archived by institutions like European Molecular Biology Laboratory. Crystallographic or three-dimensional conformational data may be deposited with repositories operated by Cambridge Crystallographic Data Centre.

Synthesis and Production

Commercial synthesis routes attributed to the compound designated E288 are described in patents filed with offices such as the European Patent Office and United States Patent and Trademark Office, and in industrial chemistry literature published by houses like Wiley-VCH and Elsevier. Production methods can involve catalytic processes using metals or organocatalysts documented in journals like Journal of the American Chemical Society, Angewandte Chemie, and Chemical Reviews. Scale-up, purification, and quality control procedures follow standards set by bodies such as Good Manufacturing Practice guidance from the World Health Organization and analytical standards from International Electrotechnical Commission. Raw material sourcing, reagent specifications, and environmental controls are often addressed in industry guidance from associations such as European Chemical Industry Council.

Uses and Applications

The E288-designated substance is employed in formulations and products specified in technical dossiers from manufacturers and industry groups including Nestlé, Unilever, Coca-Cola Company, and Kraft Heinz where applicable. Applications span preservation and stabilization roles in processed products cataloged by Food and Agriculture Organization reports, inclusion in ingredient lists regulated by European Commission directives, and use in industrial processes referenced in standards from British Standards Institution. Related sectors documenting application examples include the flavor and fragrance industry represented by International Fragrance Association, pharmaceutical excipient registries like those maintained by Pharmaceutical Research and Manufacturers of America, and cosmetic ingredient listings overseen by Cosmetics Europe.

Safety, Toxicology, and Regulation

Toxicological data for the compound linked to E288 are summarized in risk assessments by agencies such as European Food Safety Authority, Joint FAO/WHO Expert Committee on Food Additives, and national authorities like Food and Drug Administration and Health Canada. Studies published in journals including Toxicology, Food and Chemical Toxicology, and Regulatory Toxicology and Pharmacology report acute, subchronic, and chronic endpoints, along with genotoxicity, reproductive toxicity, and carcinogenicity evaluations. Regulatory status, acceptable daily intake levels, labeling requirements, and maximum usage limits are stipulated in statutes and directives from bodies such as the European Commission, Food and Drug Administration, and national legislatures; enforcement and monitoring are conducted by agencies like European Food Safety Authority and Food Standards Agency. Occupational exposure limits and workplace safety guidance are provided by institutions including Occupational Safety and Health Administration and European Agency for Safety and Health at Work.

Category:Food additives