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| Developmental Cell | |
|---|---|
| Title | Developmental Cell |
| Discipline | Developmental biology |
| Abbreviation | Dev. Cell |
| Publisher | Cell Press |
| Country | United States |
| History | 2001–present |
| Frequency | Monthly |
| Impact | 18.7 |
Developmental Cell Developmental Cell is a peer-reviewed scientific journal focusing on embryology, cell biology, molecular biology, genetics, and biochemistry. Founded in 2001 and published by Cell Press, the journal publishes original research, reviews, and perspectives that bridge studies from model organisms such as Drosophila melanogaster, Danio rerio, Mus musculus, and Caenorhabditis elegans to human developmental processes and disease-related mechanisms. Its articles frequently intersect with work from institutions like the Howard Hughes Medical Institute, Max Planck Society, Broad Institute, and universities such as Harvard University and Stanford University.
Developmental Cell covers research on cell fate, tissue morphogenesis, stem cell biology, and signaling pathways including investigations into Notch signaling, Wnt signaling pathway, Hedgehog signaling pathway, TGF-beta signaling, and Hippo signaling pathway. The journal links mechanistic studies on proteins such as p53, β-catenin, STAT3, and SMADs with organismal development in systems studied at centers like the Salk Institute for Biological Studies and the Whitehead Institute. It targets audiences at journals and societies including Nature, Science, Cell (journal), Proceedings of the National Academy of Sciences, EMBO Journal, and the American Society for Cell Biology community.
Launched in 2001 under the auspices of Cell Press, Developmental Cell emerged during a period when journals such as Genes & Development and Development were expanding coverage of molecular developmental studies. Early editorial leadership included editors drawn from laboratories affiliated with Massachusetts Institute of Technology, University of Cambridge, University of California, San Francisco, and Columbia University. Over time, publication practices adapted to shifts exemplified by initiatives at National Institutes of Health and mandates from agencies like the Wellcome Trust and the European Research Council regarding data sharing and open access. Special issues and thematic series have been organized around conferences such as the Gordon Research Conferences and meetings held by the International Society for Stem Cell Research.
The journal emphasizes mechanistic insights into developmental phenomena across taxa including zebrafish, Xenopus laevis, and Arabidopsis thaliana as well as clinical connections to congenital disorders of glycosylation, neurodevelopmental disorders, and cancer metastasis. Citation metrics place it among influential titles alongside Developmental Biology, Cell Stem Cell, and Nature Cell Biology. Authors affiliated with funding bodies such as European Molecular Biology Organization, UK Research and Innovation, and Canadian Institutes of Health Research frequently publish in the journal. Its impact is further reflected in how work cited from labs at Johns Hopkins University, Yale University, University of Chicago, and Princeton University informs translational efforts at companies like Genentech and initiatives at National Cancer Institute.
The editorial board comprises senior scientists from institutions including University of Oxford, Max Planck Institute of Molecular Cell Biology and Genetics, University of Toronto, and ETH Zurich. Manuscript handling follows peer-review workflows similar to those at Nature Communications and eLife, with policies addressing conflicts of interest, data availability, and image integrity. The journal participates in cross-publisher efforts alongside Committee on Publication Ethics and CrossRef to enforce ethical standards. It adheres to reporting guidelines favored by funders such as Gates Foundation when applicable and implements editorial decisions influenced by community standards articulated at meetings like the Society for Developmental Biology annual conference.
Developmental Cell is indexed in bibliographic services including PubMed, Web of Science, Scopus, EMBASE, and Google Scholar. Metadata are integrated with resources such as ORCID and ResearcherID to facilitate author identification, and the journal’s DOI assignments are registered through CrossRef. Libraries at institutions like Cornell University Library, Bibliothèque nationale de France, and Bodleian Libraries provide subscriptions and archival access.
The journal has published landmark studies elucidating mechanisms of asymmetric cell division, polarity establishment mediated by PAR proteins, and stem cell niche regulation involving BMP signaling. Influential reviews and research articles have come from laboratories led by researchers affiliated with Cold Spring Harbor Laboratory, University College London, and Institut Pasteur. Key contributions have connected developmental signaling to oncogenesis via studies implicating PI3K/AKT pathway dysregulation and reports on regeneration drawing on work with planarian models and vertebrate limb development research originating from groups such as those at University of Cambridge and Karolinska Institutet.
As with many high-profile journals, Developmental Cell has faced debates over reproducibility tied to high-impact claims originating from competitive groups at institutions like MIT and Harvard Medical School. Retractions and corrections have involved authors from diverse universities, with investigations sometimes coordinated by offices such as the Office of Research Integrity and university research integrity offices at Stanford University and University of California, Berkeley. The journal’s response mechanisms align with practices recommended by Committee on Publication Ethics and have included published corrigenda, expressions of concern, and retraction notices when warranted.
Category:Biology journals