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| Cambridge University Hospitals NHS Foundation Trust Research and Development Office | |
|---|---|
| Name | Cambridge University Hospitals NHS Foundation Trust Research and Development Office |
| Type | Research administration |
| City | Cambridge |
| Country | England |
| Affiliations | University of Cambridge, Addenbrooke's Hospital, Royal Papworth Hospital |
Cambridge University Hospitals NHS Foundation Trust Research and Development Office The Cambridge University Hospitals NHS Foundation Trust Research and Development Office supports clinical and translational research across Cambridge, integrating work with institutions such as University of Cambridge, Imperial College London, University College London, King's College London and international partners including Harvard Medical School, Massachusetts Institute of Technology, University of Oxford and Stanford University. It provides governance, regulatory support, study coordination and research infrastructure to investigators from centres such as Addenbrooke's Hospital, Royal Papworth Hospital and collaborations with organisations like Wellcome Trust, Medical Research Council, National Institute for Health and Care Research and European Union programmes.
The Office acts as a hub linking clinical sites including Addenbrooke's Hospital, Royal Papworth Hospital and specialist units with academic departments at University of Cambridge faculties such as Cambridge Biomedical Campus, Cambridge Institute for Medical Research and partnerships with trusts like Cambridgeshire and Peterborough NHS Foundation Trust. Services include study setup, ethics liaison with bodies such as Health Research Authority, contract negotiation with sponsors like GlaxoSmithKline, Pfizer and AstraZeneca, and data access arrangements with providers including NHS Digital and repositories related to UK Biobank.
Rooted in the expansion of clinical research at Addenbrooke's Hospital during the late 20th century, the Office formalised functions aligned with national strategies from entities such as the Department of Health and Social Care and funding frameworks from Wellcome Trust and Medical Research Council. Milestones include integration with the Cambridge Biomedical Campus developments alongside institutions such as Cancer Research UK and the establishment of partnerships with research networks including the Clinical Research Network and international collaborations with groups like European Commission Horizon projects.
Governance structures reflect accountability to boards including Cambridge University Hospitals NHS Foundation Trust executive leadership, audit committees, and research governance bodies like the Health Research Authority and institutional review boards linked to University of Cambridge faculties. Senior leadership liaises with funders such as National Institute for Health and Care Research, Wellcome Trust, and commercial partners including Roche and Novartis. Operational units coordinate with clinical specialties represented in units such as Papworth Heart Centre, Cambridge Centre for Brain Repair and biomedical partnerships with Addenbrooke's Charitable Trust.
The Office supports research spanning specialties anchored at local centres: translational oncology linked to Cancer Research UK, neuroscience with ties to MRC Cognition and Brain Sciences Unit, cardiology associated with Royal Papworth Hospital, infectious diseases aligned with Cambridge Institute for Therapeutic Immunology and Infectious Disease, and genomics collaborations with Wellcome Sanger Institute and European Bioinformatics Institute. Other domains include transplant research connected to NHS Blood and Transplant, regenerative medicine collaborating with Stem Cell Institute, and population health studies interfacing with UK Biobank and longitudinal cohorts managed by Cambridge Centre for Ageing and Neuroscience.
The Office coordinates Phase I–IV trials with academic sponsors such as University of Cambridge investigators and commercial sponsors including GSK, AstraZeneca and Sanofi. It manages trial approvals with regulators such as the Medicines and Healthcare products Regulatory Agency and ethical review via the Health Research Authority Research Ethics Committees, and fosters multi-centre consortia with networks like the Clinical Research Network and international trials involving partners such as European Medicines Agency initiatives and US collaborations with NIH-funded groups.
Funding portfolios combine competitive grants from bodies such as the Medical Research Council, Wellcome Trust, National Institute for Health and Care Research and industry contracts with companies including Pfizer and Roche. Infrastructure oversight includes clinical research facilities, biobanks coordinated with UK Biobank standards, digital platforms interoperable with NHS Digital systems, and shared laboratory resources linked to Cambridge Biomedical Campus cores and national infrastructures like the UK Research and Innovation supported initiatives.
Training for investigators, research nurses and trial managers incorporates programmes tied to University of Cambridge postgraduate offerings, NIHR training schemes, and professional development from organisations like Royal College of Physicians and Royal College of Nursing. The Office supports commercialization pathways through technology transfer links with Cambridge Enterprise, incubators such as Babraham Research Campus adjacent centres, and innovation partnerships with venture investors connected to Cambridge Science Park and translational accelerators.
Outputs include peer-reviewed publications authored by teams affiliated with University of Cambridge, translational therapies developed in partnership with Cancer Research UK and device trials linked to Royal Papworth Hospital. Notable projects involve multi-centre studies funded by Wellcome Trust and NIHR, genomics initiatives in concert with the Wellcome Sanger Institute, and pandemic-response trials aligned with Public Health England and international consortia involving WHO stakeholders. The Office's role has enabled cross-institutional achievements with collaborators including Addenbrooke's Hospital, Royal Papworth Hospital, MRC Human Immunology Unit and industry partners such as Novartis.
Category:Medical research organizations in the United Kingdom