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Biochemistry (journal)

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Biochemistry (journal)
TitleBiochemistry
DisciplineBiochemistry
AbbreviationBiochem.
PublisherAmerican Chemical Society
CountryUnited States
History1962–present
FrequencyWeekly
Impact3.7
Impact-year2023
Issn0006-2960

Biochemistry (journal) is a peer-reviewed scientific journal covering research in the chemical processes within and related to living organisms. Established in 1962, it publishes original research articles, reviews, and perspectives that intersect with molecular biology, enzymology, and structural biology. The journal is published by the American Chemical Society and is read by researchers at institutions such as the Massachusetts Institute of Technology, Harvard University, Stanford University, California Institute of Technology, and the Max Planck Society.

History

The journal was launched in 1962 during a period of rapid growth in biochemical research related to the postwar expansion of laboratories at the National Institutes of Health, Cold Spring Harbor Laboratory, and the Salk Institute. Early editorial leadership drew contributors from institutions like the Rockefeller University, Yale University, and the University of Cambridge, reflecting influence from figures associated with the Royal Society and the American Academy of Arts and Sciences. Throughout the 1970s and 1980s the journal published work from researchers affiliated with Princeton University, Johns Hopkins University, and the University of California system, paralleling developments tied to the discovery of restriction enzymes, the advent of sequencing efforts at the Wellcome Trust, and structural advances exemplified by laboratories at the European Molecular Biology Laboratory and the Francis Crick Institute. The 1990s and 2000s saw expanded coverage of membrane proteins studied at Cold Spring Harbor Laboratory and enzyme mechanisms probed at the Max Planck Institute for Biophysical Chemistry. In the 2010s and 2020s the journal has engaged with researchers from institutions such as the Broad Institute, Scripps Research, and the Howard Hughes Medical Institute, reflecting interdisciplinary collaborations with teams at ETH Zurich and the University of Tokyo.

Scope and Topics

The journal covers experimental and theoretical studies involving proteins, nucleic acids, lipids, carbohydrates, and small molecules as investigated at the molecular level. Topics frequently include enzyme kinetics and mechanism papers from laboratories at the University of Oxford and the University of Chicago, structural studies using crystallography and cryo-EM performed at the Diamond Light Source and the European Synchrotron Radiation Facility, and spectroscopy-based investigations from groups at the University of California, Berkeley and Columbia University. Articles often intersect with work on signal transduction reported from the Whitehead Institute, metabolic pathway analyses from the Pasteur Institute, and computational studies from researchers at Carnegie Mellon University and Princeton University. The journal also publishes reviews touching on themes advanced by researchers at the Rockefeller University, Cold Spring Harbor Laboratory, and Imperial College London.

Publication and Editorial Information

Published weekly by the American Chemical Society, the journal uses a single-blind peer-review model managed by an editorial board composed of scientists from institutions including the University of Cambridge, Massachusetts Institute of Technology, University of California, San Francisco, and Kyoto University. Editors coordinate with advisory members from the National Academy of Sciences, Royal Society, and the European Molecular Biology Organization. The submission process integrates manuscript handling systems employed by publishers such as Wiley and Elsevier, while editorial decisions are informed by external referees drawn from universities such as Duke University, Johns Hopkins University, and the University of Toronto. Special issues and themed collections have been guest-edited by investigators affiliated with the Max Planck Society and the Howard Hughes Medical Institute.

Abstracting and Indexing

The journal is indexed in major bibliographic databases including MEDLINE/PubMed, Chemical Abstracts Service, Scopus, and the Web of Science Core Collection. It is included in citation metrics compiled by Clarivate Analytics and bibliometric aggregations used by institutions like the Wellcome Trust and the National Science Foundation. Abstracting services operated by organizations such as ProQuest and EBSCO list the journal, and article metadata are harvested by aggregators tied to CrossRef and ORCID for researcher identification and citation linking.

Impact and Reception

The journal has maintained a steady impact within the biochemical community, cited in landmark studies from laboratories at the Salk Institute, University of California, San Diego, and RIKEN. Coverage in review articles and meta-analyses from teams at the University of Pennsylvania, Yale University, and the University of Michigan frequently references its contributions to enzymology and protein chemistry. Awards and recognition associated with work published in the journal include later honors such as Lasker Awards, Nobel Prizes, and membership in national academies for authors affiliated with institutions like the Karolinska Institutet and the Pasteur Institute. Critical reception emphasizes methodological rigor and relevance to experimentalists at the European Molecular Biology Laboratory and the Whitehead Institute.

Notable Articles and Contributions

Over its history the journal has published influential reports on enzyme catalytic mechanisms from groups at the University of Chicago and Harvard Medical School, structural elucidations of protein folds by researchers at the MRC Laboratory of Molecular Biology and the Max Planck Institute, and methodological advances in isotope labeling and kinetic analysis from laboratories at the University of California, Los Angeles and the University of Wisconsin–Madison. Seminal reviews synthesizing work on ribonucleoprotein complexes and transcriptional machinery have cited contributions from the Cold Spring Harbor Laboratory and EMBL. Articles introducing novel spectroscopic probes and cross-linking strategies originated from collaborations involving the Scripps Research Institute and the University of North Carolina at Chapel Hill.

Access and Availability

The journal is available through institutional subscriptions held by university libraries at Harvard University, Stanford University, and the University of Cambridge, and through consortia agreements managed by organizations such as Jisc and the Association of Research Libraries. Authors may choose open access options compatible with funder mandates from the Wellcome Trust, Bill & Melinda Gates Foundation, and the National Institutes of Health, enabling deposition in repositories like PubMed Central and institutional archives at Columbia University and the University of Oxford. Back issues are archived in national libraries including the Library of Congress and the British Library.

Category:Biochemistry journals Category:American Chemical Society journals